Most people may have known bitcoin by then and may have transacted or have own at least some btcs during that time. I don't think its possible how firm fiat's hold in the market and its accessibility. But i think its highly possible that most people may have accessed btc by then
Fiat will always be around, and I think it won't disappear, with this high transaction fees,practically, everyone would be using fiat than pay for each transaction they made.
2022 is still far, but if you look at the social media and others, you could always find a talk about bitcoin, including those big ones, they are now talking about bitcoin, so when it comes to spread of knowledge about it, I think it won't take long, but when it comes to use, I think it will take time.