1. Do you need a structured central repository of information?
2. Is more than one entity reading or writing transactions to a database?
3. Is there less than total trust between parties/entities in the ecosystem (for example, one user will not accept the "truth" as reported by another user)?
4. Are central gatekeepers introducing costs andor "friction" when verifying transactions (for example, manual verification)?
5. Are there routine or logical interactions that occur that could be programmed to self-execute (for example, smart contracts)?