If bitcoin reaches a price whereby I can purchase a house for 10 BTC without having to take out a 25 year mortgage.
I'll get out, and into something else.
If it was possible to do so, I'd also buy the house with BTC otherwise I'd have to cash out into fiat first to make the purchase.
I generally favor buying things with bitcoin rather than converting to fiat, but in the case of a large purchase like a house, you might be better off taking out a mortgage. Inflation is good for debtors. You could pay 10 BTC at the time of purchase, or you could take out a fiat mortgage. Maybe you would have to convert 1 BTC to fiat for the down payment and first year mortgage payments, but in the second year the amount of bitcoin you would need to convert to fiat would be less because bitcoin's value relative to fiat would have risen, and each year thereafter your bitcoin cost to pay the mortgage would be less and less, so that by the end of the 25 years you would have paid less than the 10 BTC would have paid to buy the house at the beginning. Sorry, I think that was a run-on sentence.