uBlock Origin and
uMatrix (same author) is one of the best must have combos any browser should always have.
Adblock should not be used. You can pay the author to let some ads pass, that's quite absurd, it shouldn't even be mentioned.
uBlock is an ad blocker done right (and lighter). What is uMatrix? Freedom. I mean, you can either whitelist or blacklist "things" from pages, domains etc. What things? Things like cookies, css, images, media, script, XHR, frame, other. YOU are in control of your browser, not them.
The net isn't safe, and browsers shouldn't be naively used without these basic protections. Of course a secure OS and a secure browser are always recommended, in addition to these.
Browsers are basically divided in two families: Firefox and Chromium. For both families these addons/extensions exist.
Ungoogled-chromium and
LibreWolf should be considered by privacy concerned people. Tor browser is also great but its on a whole new level.