I am not seeing the Fed chair Jerome Powell as a big problem for Trump's actualisation of making bitcoin a reserve for the US, but rather it's the Congress house I am most concerned about . The congressional has so much to wield on this matter and if they get to be on bitcoin's favour then Powell has no say but otherwise then that's a big problem for Trump.
It's not that Jerome Powell doesn't have a say, it's just that if this proposal is passed by Congress, it means Jerome Powell needs to comply, he can go against Trump but he can't go against the US Constitution. Just like when Trump wanted to have a Bitcoin reserve, this also requires Congressional approval, if it is vetoed by Congress, there is nothing Trump can do to reverse it. Congress is the place to enforce the national constitution and no one can oppose even Trump.
In recent news now it is said that the US government under Joe Biden are planning on selling $6.5 billion worth of seized BTC just in same way Germany government did in mid 2024. All this coming at a time when Trump has proposed on making bitcoin a reserve. It's possible that this sell is to truncate Trump's success with the reserve idea as this sells could actually discourage Congress members towards pitching on Trump's idea of a bitcoin reserve seeing how bitcoin could dump with this sell. Although the market will surely recover later, but not every politician thinks in that direction.
Even if the US government owned more bitcoin, that wouldn't increase the chances of Trump's bitcoin reserve idea succeeding. Because the Fed and Congress will value bitcoin based on many factors because national reserves are important, not based on how much bitcoin the US government owns. That's why Powell said he's not interested in bitcoin because it doesn't meet the standards they need.
The Fed is an independent agency whose mission and job is to regulate the U.S. and world economies through monetary policies and ensure economic stability. They are unconcerned and unaffected by the political rivalry in the White House.