Even if Ghana is the first country in Africa to legalize bitcoin, that doesn't make them the cryptocurrency hub in Africa.
Not every country that is a pioneer in legalizing and adopting bitcoin and crypto automatically becomes a crypto hub. Like El Salvador, they were the first country to make bitcoin legal tender as well as the most crypto friendly country when the world was skeptical about it. But are they the crypto hub of the world? No, they are not.
To be able to become a regional or world crypto hub, they need to have large scale and comprehensive like friendly legal framework, strong infrastructure and technology. They need to create a friendly environment to attract domestic and foreign investment...and many other factors. This is not easy as it requires a lot of money and resources to do. Therefore, countries with strong economies will have more potential.
A nation can make noise regionally and globally by pioneering in something like El Salvador and their Bitcoin legal tender initiative in 2020 and attempt to build up their Bitcoin Beach Village months later in that year, but it's only enough for making noise, and gain some sort of short term effects.
In order to be a hub in any industry, there must be enough infrastructures behind the scene which need to be already existed in that nation or location before any initiative. Like nations in the Middle East, which are rich but more than that, they actually have very good foundations from economy, transportation, environment before they legalize Bitcoin and cryptocurrencies for becoming a hub of blockchain and cryptocurrencies in the Asia and somewhat globally too.
Ghana is not a rich nation but it does not have solid available foundations like Middle-East nations so it's impossible for Ghana to become a hub of blockchain and cryptocurrency industry in the Africa continent in the near future.