It's even alarming that it has reached that level since the 45%, although still a minority, includes institutions that are catching up, they are buying Bitcoin to potentially dominate the market in the future. What was once pseudonymous, I'm afraid we might not fully enjoy that privacy in the future if we are forced to use centralized systems to exchange our Bitcoin, governments are doing everything they can to make it operate more like a bank, and they are undermining the nature of decentralization with their centralized regulations.
Since the latest market cycle, there was discussion about less effects from Bitcoin halving and Bitcoin miners because most bitcoins in total supply have been already mined. There is not too considerable percent of Bitcoin total supply to be mined in future Bitcoin blocks till 2140, it's one thing.
Another thing is appearance and participation of more institutions in Bitcoin market. They have bigger capital, more long term vision and strategy for their investment, then they have gradually collected bitcoins from miners and retail investors. With time, years, cycles especially bear markets, more bitcoins will be owned and centralized in institutions.
Fortunately, if you can realize this wide picture, you can make your own strategy for investment portfolio and enjoy good profit in future years, cycles and decades.