amd mining is usually more tricky than nvidia :
- with nvidia, most of the time, you just use the lattest driver, one miner among ccminer (open source), ccminer spmod (closed source with some optimisation for some algos, you must pay), eventually an ethminer and equihash one, then you play with the intensity and the overclock and that's all.
- with amd: this is more tricky : you must use the right software, with a modded bios or a registry hack, with the good miner (depends on the algo) and mine the right coin: you have less algo choice than nvidia, but amd is better for eth dual mining and xmr/aeon. Then you need to restart the driver/miner for various reasons (change of parameter, use of 3d program ...) to keep a good hashrate.
I could add my experience. I'm running rigs of 8xVega56. But it took me two weeks to find a stable configuration and optimize everything. Bios flash, registry hacks, dealing with dark options on monitoring software to prevent hangs, finding the right miner and benchmarking/stress testing each vega separately to find its best profile (not all cards are equal). Some will happily accept lower voltages, others not. Some will hang under specific loads but will be rock stable with other loads. The MB too plays a role and the bios settings too.
There're guides and ready mods available. However, unless you're lucky, those will need a good amount of tweaking to adapt them to your rigs.
At the end, you can squeeze a good amount on cryptonight but for other algos it's not worth the hassle.