I found out that when I exceeded 125 sticks cpu use went nuts and the 125th stick read endless errors. not sure if the pc or bitminter software is the issue. windows 7 has a 127 usb device limit for 1 controller. this pc has a 5 port pcie usb card with a second controller so I should be able to go to 240 sticks or even 250. So when I got past the 127 device limit the cpu went nuts and the last stick added com284 just read endless errors. in the photo below it is at 6000 and change and counting up really fast
This is a controller limit not a port limit as i understood it, the max is system wide 127 however this number is theoretical.
In reality each usb device connected takes one device slot, so in my view you loose 2 devices for the controller leaving you with 125 devices to connect.
I did not check if the hubs are seen as shared devices
I am not sure if the professional hardware solutions which you can buy can run more but those are very expenssive and contain very good components, but if they are just loaders or can run devices like needed for mining is not clear to me.