Yes, this question is certainly on the mind of almost everyone who holds BTC.
On the one hand, it is very good for the market and acceptance if the BTC also arrive in payment transactions. But I can also understand that at the current time people are a bit more cautious. Nobody wants to have paid 300 dollars for their coffee in a year. That is a kind of question of faith that everyone must answer for themselves.

It depends on what you are referring to as Spending Bitcoin. Do you mean, spend direct Bitcoin on the purchase or spend out of your Bitcoin by converting to fiat?. Whichever way I believe that both are still spending Bitcoin and many investors including myself most have done one of this. I don't directly spend BTC but do take some profits whenever I am really in need of funds and mostly HODLing the rest.

Well yes, I've been holding bitcoin in the past and used it to buy certain assets that will let my family live comfortable than we used to be almost a decade ago when I didn't know about bitcoin yet. And nope, I didn't regret anything about what I spent because it really helped me and family.
For now, I'm trying to maximize my portfolio again by holding bitcoin and altcoins, I do side tradings like weekly to gain something and put it back in BTC and ETH. I'm trying to hold as much as possible until the time that I needed to sell it again.

Yes.

What I like to do though, is that every time I spend some bitcoin, I also buy bitcoin with fiat, at least the same amount, usually more.

So, by using this technique, I am actually increasing the amount of bitcoin that I have every time that I buy something with bitcoin. Win/Win.

if you spend Bitcoin you don’t miss out on gains, but on potential gains, but you also reduce potential losses (aka risks). Some people cash out, some people trust and hodl. I pay with bitcoin to spread the word!