Based on these possibilities, what do you think will happen in some decades when many of the private keys are lost?
Scarcity with huge demand drives the price up. By then Bitcoin will be very valuable. The more Bitcoin is lost, the scarcer it became thus the possibility of price skyrocketing is very possible.
What of when nearly all are lost?
If all are nearly lost, I think it will become a collector's item just like the ancient relics, a legacy that worth possibly billions to trillions per coins
Even though we may not know when this would be, I wonder what will happen when they're all lost.
Bitcoins that are lost or inaccessible will just sit idly on the address, unless the developer consent an update to claim lost coin.
If you die today, will your coins be lost?
Depends, if the person prepared for the family to know his private key when he passed away, the coins won't be lost, but if there are no other people knows his passphrase, then that coins might be lost.